| Rank | Player | Sacks |
|---|---|---|
| T-1 | T.J. WattPittsburgh Steelers · LB | 7.5 |
| T-1 | Will Anderson Jr.Houston Texans · DE | 7.5 |
| T-3 | Chase YoungNew Orleans Saints · DE | 7.0 |
| T-3 | Greg RousseauBuffalo Bills · LB | 7.0 |
| T-5 | Andrew Van GinkelMinnesota Vikings · LB | 6.5 |
| T-5 | Jacob MartinTennessee Titans · DE | 6.5 |
| T-7 | Dallas TurnerMinnesota Vikings · LB | 6.0 |
| T-7 | Elijah PonderNew England Patriots · LB | 6.0 |
| T-9 | Boye MafeCincinnati Bengals · DE | 5.5 |
| T-9 | Carl GrandersonNew Orleans Saints · DE | 5.5 |
| T-9 | David BaileyNew York Jets · LB | 5.5 |
| T-12 | Aidan HutchinsonDetroit Lions · DE | 5.0 |
| T-12 | Dexter Lawrence IICincinnati Bengals · DT | 5.0 |
| T-12 | DJ WonnumDetroit Lions · LB | 5.0 |
| T-12 | Jeffery SimmonsChicago Bears · DT | 5.0 |
| T-12 | Quinnen WilliamsDallas Cowboys · DT | 5.0 |
| T-17 | Alim McNeillDetroit Lions · DT | 4.5 |
| T-17 | Blake CashmanMinnesota Vikings · LB | 4.5 |
| T-17 | Byron YoungLos Angeles Rams · LB | 4.5 |
| T-17 | Lukas Van NessGreen Bay Packers · DE | 4.5 |
| T-17 | Za'Darius SmithAtlanta Falcons · DE | 4.5 |
| T-17 | Zach AllenDenver Broncos · DE | 4.5 |
| T-23 | Adetomiwa AdebaworeIndianapolis Colts · DT | 4.0 |
| T-23 | Austin BookerChicago Bears · DE | 4.0 |
| T-23 | Chop RobinsonMiami Dolphins · LB | 4.0 |
| T-23 | Danielle HunterHouston Texans · DE | 4.0 |
| T-23 | David WalkerTampa Bay Buccaneers · LB | 4.0 |
| T-23 | DeForest BucknerIndianapolis Colts · DT | 4.0 |
| T-23 | Jalen CarterPhiladelphia Eagles · DT | 4.0 |
| T-23 | Kyler GordonChicago Bears · CB | 4.0 |
| T-23 | Mason GrahamCleveland Browns · DT | 4.0 |
| T-23 | Nolan Smith Jr.Philadelphia Eagles · LB | 4.0 |
| T-23 | Odafe OwehWashington Commanders · LB | 4.0 |
| T-34 | Adin HuntingtonCleveland Browns · DE | 3.5 |
| T-34 | Alex HighsmithPittsburgh Steelers · LB | 3.5 |
| T-34 | Budda BakerArizona Cardinals · S | 3.5 |
| T-34 | Christian BarmoreNew England Patriots · DT | 3.5 |
| T-34 | K'Lavon ChaissonWashington Commanders · LB | 3.5 |
| T-34 | Keion WhiteSan Francisco 49ers · DE | 3.5 |
| T-34 | Malcolm RoachDenver Broncos · DT | 3.5 |
| T-34 | Maliek CollinsCleveland Browns · DT | 3.5 |
| T-34 | Mike GreenBaltimore Ravens · LB | 3.5 |
| T-34 | Nik BonittoDenver Broncos · LB | 3.5 |
| T-34 | Tavius RobinsonBaltimore Ravens · LB | 3.5 |
| T-45 | Byron Murphy IISeattle Seahawks · DT | 3.0 |
| T-45 | Dayo OdeyingboChicago Bears · DE | 3.0 |
| T-45 | Derick HallSeattle Seahawks · LB | 3.0 |
| T-45 | Derrick BarnesDetroit Lions · LB | 3.0 |
| T-45 | Devonte WyattGreen Bay Packers · DT | 3.0 |
| T-45 | Edgerrin CooperGreen Bay Packers · LB | 3.0 |
Regular season, from ESPN, refreshed hourly. Every stat