

| Rank | Player | Rush Yds |
|---|---|---|
| 1 | Bijan RobinsonAtlanta Falcons · RB | 780 |
| 2 | Jahmyr GibbsDetroit Lions · RB | 773 |
| 4 | Bucky IrvingTampa Bay Buccaneers · RB | 728 |
| 11 | Kyren WilliamsLos Angeles Rams · RB | 548 |
| 12 | D'Andre SwiftChicago Bears · RB | 545 |
| 13 | Chuba HubbardCarolina Panthers · RB | 540 |
| 14 | Javonte WilliamsDallas Cowboys · RB | 528 |
| 16 | Aaron Jones Sr.Minnesota Vikings · RB | 458 |
| 17 | Cam SkatteboNew York Giants · RB | 418 |
| 19 | Emanuel WilsonSeattle Seahawks · RB | 403 |
| T-20 | Blake CorumLos Angeles Rams · RB | 389 |
| T-20 | Christian McCaffreySan Francisco 49ers · RB | 389 |
| 26 | Kyle MonangaiChicago Bears · RB | 324 |
| 27 | Tyler AllgeierArizona Cardinals · RB | 323 |
| 30 | Kenny GainwellTampa Bay Buccaneers · RB | 289 |
| 32 | Saquon BarkleyPhiladelphia Eagles · RB | 274 |
| 35 | Jeremiyah LoveArizona Cardinals · RB | 268 |
| 36 | Jacory Croskey-MerrittWashington Commanders · RB | 239 |
| 38 | Kaelon BlackSan Francisco 49ers · RB | 233 |
| 42 | Brian Robinson Jr.Atlanta Falcons · RB | 211 |
| 45 | Rachaad WhiteWashington Commanders · RB | 200 |
| 49 | Bam KnightArizona Cardinals · RB | 168 |
| 54 | Kendre MillerNew Orleans Saints · RB | 159 |
| 56 | MarShawn LloydGreen Bay Packers · RB | 149 |
| 57 | Jadarian PriceSeattle Seahawks · RB | 148 |
| 58 | Jordan MasonMinnesota Vikings · RB | 147 |
| 66 | Travis Etienne Jr.New Orleans Saints · RB | 128 |
| 68 | Alvin KamaraNew Orleans Saints · RB | 125 |
| 70 | Sione VakiDetroit Lions · RB | 121 |
| 71 | George HolaniSeattle Seahawks · RB | 117 |
| 76 | Kaleb JohnsonGreen Bay Packers · RB | 104 |
| 77 | Roschon JohnsonChicago Bears · RB | 103 |
| 79 | Najee HarrisNew York Giants · RB | 99 |
| 80 | Dameon PiercePhiladelphia Eagles · RB | 96 |
| 81 | Tank BigsbyPhiladelphia Eagles · RB | 91 |
| 84 | Tyler GoodsonDallas Cowboys · RB | 86 |
| 85 | CJ DonaldsonNew Orleans Saints · RB | 81 |
| T-86 | Devin SingletaryNew York Giants · RB | 80 |
| T-86 | Sean TuckerTampa Bay Buccaneers · RB | 80 |
| T-95 | Josh JacobsGreen Bay Packers · RB | 75 |
| T-99 | Chris BrooksGreen Bay Packers · RB | 70 |
| 101 | Austin EkelerWashington Commanders · RB | 67 |
| 104 | Will ShipleyPhiladelphia Eagles · RB | 57 |
| 105 | Tyrone Tracy Jr.New York Giants · RB | 55 |
| 111 | Elijah MitchellPhiladelphia Eagles · RB | 45 |
| T-113 | AJ DillonCarolina Panthers · RB | 43 |
| T-122 | Pierre Strong Jr.Green Bay Packers · RB | 37 |
| T-125 | Jeremy McNicholsWashington Commanders · RB | 34 |
| 131 | Jonathon BrooksCarolina Panthers · RB | 30 |
| T-135 | Velus Jones Jr.Seattle Seahawks · RB | 28 |
Regular season, from ESPN, refreshed hourly. Every stat