| Rank | Player | Tackles |
|---|---|---|
| T-568 | James Thompson Jr.San Francisco 49ers · DT | 9 |
| T-568 | Kentavius StreetChicago Bears · DT | 9 |
| T-568 | Sebastian ValdezSan Francisco 49ers · DT | 9 |
| T-596 | Joshua FarmerNew England Patriots · DT | 8 |
| T-596 | Kris Jenkins Jr.Cincinnati Bengals · DT | 8 |
| T-596 | LT OvertonDallas Cowboys · DT | 8 |
| T-596 | Mike Hall Jr.Cleveland Browns · DT | 8 |
| T-596 | Nazir StackhouseTennessee Titans · DT | 8 |
| T-596 | T.J. SandersBuffalo Bills · DT | 8 |
| T-596 | TeRah EdwardsCarolina Panthers · DT | 8 |
| T-596 | Timmy HorneTennessee Titans · DT | 8 |
| T-636 | Andrew BillingsArizona Cardinals · DT | 7 |
| T-636 | Bobby Brown IIICarolina Panthers · DT | 7 |
| T-636 | Broderick Washington Jr.Baltimore Ravens · DT | 7 |
| T-636 | Christian BarmoreNew England Patriots · DT | 7 |
| T-636 | Darius AlexanderNew York Giants · DT | 7 |
| T-636 | Neville GallimoreChicago Bears · DT | 7 |
| T-636 | Rylie MillsSeattle Seahawks · DT | 7 |
| T-636 | Tershawn WhartonCarolina Panthers · DT | 7 |
| T-636 | Ty HamiltonLos Angeles Rams · DT | 7 |
| T-685 | Anthony CampbellGreen Bay Packers · DT | 6 |
| T-685 | Jaden CrumedyHouston Texans · DT | 6 |
| T-685 | Javon HargraveGreen Bay Packers · DT | 6 |
| T-685 | Leonard Taylor IIINew England Patriots · DT | 6 |
| T-685 | Mario Edwards Jr.Houston Texans · DT | 6 |
| T-685 | Tim SmithIndianapolis Colts · DT | 6 |
| T-685 | Tyler LacyDetroit Lions · DT | 6 |
| T-733 | Bobby Jamison-TravisNew York Giants · DT | 5 |
| T-733 | C.J. WestSan Francisco 49ers · DT | 5 |
| T-733 | Christen MillerNew Orleans Saints · DT | 5 |
| T-733 | CJ OkoyeNew York Giants · DT | 5 |
| T-733 | DaQuan JonesNew England Patriots · DT | 5 |
| T-733 | Domonique OrangeMinnesota Vikings · DT | 5 |
| T-733 | Elijah SimmonsTampa Bay Buccaneers · DT | 5 |
| T-733 | Jonah LauluLas Vegas Raiders · DT | 5 |
| T-733 | Jonathan FordGreen Bay Packers · DT | 5 |
| T-733 | Kayden McDonaldHouston Texans · DT | 5 |
| T-733 | Rakeem Nunez-RochesTampa Bay Buccaneers · DT | 5 |
| T-733 | Ty RobinsonPhiladelphia Eagles · DT | 5 |
| T-782 | JJ PeguesLas Vegas Raiders · DT | 4 |
| T-817 | Jack HeflinNew York Jets · DT | 3 |
| T-817 | John Ridgeway IIINew Orleans Saints · DT | 3 |
| T-817 | Jonathan BullardDallas Cowboys · DT | 3 |
| T-817 | Kenneth GrantMiami Dolphins · DT | 3 |
| T-817 | Shemar TurnerChicago Bears · DT | 3 |
| T-817 | Tim Keenan IIILas Vegas Raiders · DT | 3 |
| T-871 | Albert RegisJacksonville Jaguars · DT | 2 |
| T-871 | Brandon PiliSeattle Seahawks · DT | 2 |
| T-871 | Bryson EasonKansas City Chiefs · DT | 2 |
| T-871 | Cam JacksonCarolina Panthers · DT | 2 |
Regular season, from ESPN, refreshed hourly. Every stat