

| Rank | Player | Tackles |
|---|---|---|
| T-147 | Calen BullockHouston Texans · S | 30 |
| T-147 | Jaylinn HawkinsBaltimore Ravens · S | 30 |
| T-147 | Jevon HollandNew York Giants · S | 30 |
| T-147 | Markquese BellDallas Cowboys · S | 30 |
| T-147 | Quan MartinWashington Commanders · S | 30 |
| T-166 | Nick ScottCarolina Panthers · S | 29 |
| T-166 | Robert Spears-JenningsPittsburgh Steelers · S | 29 |
| T-166 | Tre'von MoehrigCarolina Panthers · S | 29 |
| T-178 | Malik MustaphaSan Francisco 49ers · S | 28 |
| T-178 | Sydney BrownAtlanta Falcons · S | 28 |
| T-178 | Tony AdamsTennessee Titans · S | 28 |
| T-192 | Christian IzienDetroit Lions · S | 27 |
| T-192 | Malik HookerDallas Cowboys · S | 27 |
| T-199 | C.J. Gardner-JohnsonBuffalo Bills · S | 26 |
| T-199 | Cam BynumIndianapolis Colts · S | 26 |
| T-199 | Marques SigleSan Francisco 49ers · S | 26 |
| T-199 | Zakee WheatleyCarolina Panthers · S | 26 |
| T-227 | Jalen PitreHouston Texans · S | 24 |
| T-243 | Andre CiscoNew York Jets · S | 23 |
| T-243 | Damar HamlinBuffalo Bills · S | 23 |
| T-243 | Lathan RansomCarolina Panthers · S | 23 |
| T-243 | Talanoa HufangaDenver Broncos · S | 23 |
| T-261 | Chamarri ConnerKansas City Chiefs · S | 22 |
| T-261 | Nick CrossWashington Commanders · S | 22 |
| T-279 | Derwin James Jr.Los Angeles Chargers · S | 21 |
| T-279 | Theo JacksonMinnesota Vikings · S | 21 |
| T-279 | Tyler NubinNew York Giants · S | 21 |
| T-298 | Devon KeyDenver Broncos · S | 20 |
| T-298 | Rayuan Lane IIIJacksonville Jaguars · S | 20 |
| T-315 | Jaylen McColloughLos Angeles Rams · S | 19 |
| T-337 | Ar'Darius WashingtonNew York Giants · S | 18 |
| T-362 | Jalen ThompsonDallas Cowboys · S | 17 |
| T-362 | RJ MickensLos Angeles Chargers · S | 17 |
| T-362 | Ty OkadaSeattle Seahawks · S | 17 |
| T-378 | Genesis SmithLos Angeles Chargers · S | 16 |
| T-378 | Hunter WohlerIndianapolis Colts · S | 16 |
| T-378 | Isaiah Pola-MaoLas Vegas Raiders · S | 16 |
| T-378 | Rayshawn JenkinsPittsburgh Steelers · S | 16 |
| T-397 | Eric MurrayJacksonville Jaguars · S | 15 |
| T-397 | Harrison SmithMinnesota Vikings · S | 15 |
| T-397 | M.J. StewartHouston Texans · S | 15 |
| T-397 | Rodney Thomas IISeattle Seahawks · S | 15 |
| T-397 | Terrell BurgessTennessee Titans · S | 15 |
| T-426 | Ifeatu MelifonwuTampa Bay Buccaneers · S | 14 |
| T-426 | Marcus EppsPhiladelphia Eagles · S | 14 |
| T-426 | Taylor RappDenver Broncos · S | 14 |
| T-426 | Zayne AndersonMiami Dolphins · S | 14 |
| T-453 | Dadrion Taylor-DemersonArizona Cardinals · S | 13 |
| T-480 | Alijah ClarkDallas Cowboys · S | 12 |
| T-480 | Xavier WoodsChicago Bears · S | 12 |
Regular season, from ESPN, refreshed hourly. Every stat